MaxWell Publications
Peer-reviewed science and conference abstracts documenting our progress toward a non-destructive alternative to catheter ablation.
Heart Rhythm Society (HRS) 2026
Presented at the HRS in Chicago, Illinois, April 2026
Atrial fibrillation affects more than 37 million people worldwide and remains a leading cause of stroke, heart failure, and cardiovascular morbidity. While rhythm control has demonstrated superiority over rate control, achieving acute AF termination without high-energy shock remains an unmet clinical need.
The following work was accepted for poster presentation at the Heart Rhythm Society (HRS) 2026 Annual Scientific Sessions in Chicago, IL, comparing AF termination efficacy of the closed-loop SRT adaptive algorithm versus a fixed programmed pulse sequence across patient-derived persistent AF substrates.
Published: 2026
Closed-loop Adaptive Pacing Outperforms Programmed Sequences for AF Termination.
Termination of Atrial Fibrillation via Spatial Resynchronization Therapy (SRT)
Published: 2026
Published: 2026
Left Atrial Multisite Pacing (LAMSP) Achieves Global Control, Cycle Length Prolongation and AF Termination in Atrial Fibrillation: First-in-Human Results.
European Heart Rhythm Association (EHRA) 2026
Presented at the EHRA annual congress in Paris, France, April 12th- 14th
Our team presented two posters at the European Heart Rhythm Association (EHRA) annual congress in Paris, France, highlighting our progress in developing a next-generation alternative to catheter ablation for atrial fibrillation.
Published: 2026
Left atrial multi-site pacing achieves up to 10x greater AF cycle length prolongation vs. catheter ablation.
Real-Time Global Control Index for adaptive Atrial Resynchronization: A Quantitative Mechanism for Novel AF Therapy.
Published: 2026
Heart Rhythm Society (HRS) 2022
Presented at EHRA in San Francisco, CA, 2022
An interactive, physiologically realistic (PR), and accurate computer simulation allows multiple scenarios to be tested in a “live” environment and has become a key step in the rapid development and testing of treatment strategies for atrial fibrillation (AF). Develop an accurate model of AF that allows the user to define the regions and zones of anisotropic conduction to test the effectiveness of a variety of AF treatment strategies.
Published: 2022
Physiologic, Realistic, Computer Modeling of Atrial Fibrillation to Facilitate the Development and Testing of Treatment Strategies
Scientific Reports: Nature Research
About 30% of patients with impaired cardiac function have ventricular desynchrony and seek cardiac resynchronization therapy (CRT). In this study, we demonstrate synchronized biventricular (BiV) pacing in a leadless fashion by implementing miniaturized and wirelessly powered pacemakers.
Published: 2020
Synchronized Biventricular Heart Pacing in a Closed-Chest Porcine Model Based on Wirelessly Powered Leadless Pacemakers
Heart Rhythm Society (HRS) 2019
Presented at HRS in San Francisco, CA, 2019
New advancements in pacemaker technology have pushed the field from traditional pacemakers to leadless pacemakers to mitigate risks. While current leadless pacemakers reduce the risks associated with leads, they have not been able to substantially reduce the size and weight of these pacemakers, limiting their ability to pace from multiple chambers. This proof-of-concept study shows our wirelessly powered microchip can pace the ventricular myocardium and demonstrates potential for these kinds of devices.
Published: 2019